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Drug Solubility - a challenge in pharmaceutical development

The meeting is moved to Apotekarsocieteten Wallingatan 26A in Stockholm.

An increasing fraction of new drug candidates have a poor solubility which often causes problems in terms of low and/or variable oral bioavailability. In some cases solubility will also stop promising drugs from reaching the market. For these reasons, significant research efforts are spent on understanding how to manage solubility and bioavailability problems.

 


 

Courses
Date Location Course fee (SEK excl. VAT, early/late)
» 30/9 - 30/9 Stockholm 3100/3600 SEK after 2010-09-01
Participation fee and meals The participation fee, which includes certificate of completion, coffee, lunch and coffee is SEK 3100 before September 1 and SEK 3600 after that date.
All prices given excluding VAT.
Project administrator Jenny Hagberg
jenny.hagberg@lakemedelsakademin.se
Who should attend This meeting is intended for anyone who needs an improved understanding of how to develop poorly soluble drugs into successful products.
Programme

09.00 Registration

09.30 
Analysis of poor solubility from a molecular perspective: in silico and in vitro approaches
Christel Bergström, Department of pharmacy, Uppsala university, Uppsala, Sweden

10.00 
Impact of solubility and dissolution on oral bioavailability
Gunilla Hanisch, AstraZeneca R&D Mölndal, Sweden

10.30 Coffee

11.00 
Analytical methods for poorly soluble compounds
Anders Sokolowski, AS Consulting, Uppsala, Sweden

11.30 
Salt selection for poorly soluble compounds
Tesfai Sebhatu, AstraZeneca R&D Södertälje, Sweden

12.00 Time for discussion

12.30 Lunch

13.30 
Strategic development of lipid based drug delivery systems
Anette Müllertz, University of Copenhagen, Denmark

14.00 
Pharmaceutical cocrystallization- A novel tool for improving solubility of poorly soluble drugs
Sitaram Velaga, Luleå University of Technology, Sweden

14.30 Coffee

15.00 
Nanoparticle formulations for poorly soluble compounds
Lennart Lindfors, AstraZeneca R&D, Mölndal, Sweden

15.30 
Formulation for pre-clinical studies
Björn Norrlind, Stockholm, Sweden 

16.00 Time for discussion

16.30  Mingle and refreshments
Organizing committée Torkel Gren, AstraZeneca R&D, Södertälje Christel Bergström, Dep. of Pharmacy, Uppsala University, Uppsala, Tuulikki Lindmark, Semcon Life Science, Uppsala, Anders Sokolowski, AS Consulting, Uppsala, Agneta Larhed, Läkemedelsakademin, Stockholm.
Time and location The seminar is held at Apotekarsocieteten, Wallingatan 26A, Stockholm, Thursday September 30.
Registration and cancellation

Acceptance is on a space-available basis. Cancellations can be made at no charge up until 30 days before the start of the seminar. After this our cancellation policy applies, wich can be found in the confirmation document and on our home page. Cancellations should be addressed in writing.

For questions about the programme please contact Agneta Larhed agneta.larhed@lakemedelsakademin.se phone: +46(8)-723 50 10.
For organizational questions, please contact Jenny Hagberg jenny.hagberg@lakemedelsakademin.se phone: +46(8)-723 50 08.
 



Läkemedelsakademin. Besöksadress: Wallingatan 26 A. Postadress: Box 1136, 111 81 Stockholm.
Tel: 08-723 50 00. Fax: 08-20 55 11. E-post: info@lakemedelsakademin.se